ROLE OF HUMAN KIS (HKIS) AS AN INHIBITORY KINASE OF THE CYCLIN-DEPENDENTKINASE INHIBITOR P27. COMPOSITIONS, METHODS AND USES THEREOF TO CONTROL CELL PROLIFERATION

摘要

Disclosed herein are novel composition and methods for altering theproliferation of a cell. Included are wild-type and mutant hKISpolypeptides along with cyclin kinase inhibitors containing mutations thatprevent their inhibition with serine/threonine kinases.