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BISPECIFIC MOLECULE COMPRISING LIGANDS FOR CELL-SURFACE PROTEIN AND T-CELL SURFACE PROTEIN
BISPECIFIC MOLECULE COMPRISING LIGANDS FOR CELL-SURFACE PROTEIN AND T-CELL SURFACE PROTEIN
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机译:双特异性分子,包含细胞表面蛋白和T细胞表面蛋白的配体
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摘要
The present invention provides bispecific therapeutic molecules that target both aberrant cells, such as cancer cells, as well as T cells, and compositions comprising them. The invention further provides methods of detecting aberrant cells and methods of treating subjects with one or more cancers. The bi-specific molecules of the invention bind to both the T cells and the target aberrant cells, causing them to be brought into close proximity such that the effects of the T cell can be easily localized to the target aberrant cell.
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