ANIMAL IN WHICH LIPID METABOLISM AND SUGAR METABOLISM ARE MODIFIED BY KRAP GENE MUTATION, MODIFICATION METHOD AND MODIFYING AGENT

摘要

It is intended to provide a novel agent which can contribute to prevention and/or treatment of obesity and/or diabetes, a transgenic animal which can be used for the purpose of elucidating pathologic conditions of such as obesity and/or diabetes or the like, a nucleic acid molecule which can be used for the production thereof and the like. One aspect of the invention is a transgenic nonhuman animal in which the expression of KRAP gene is reduced or lost.