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FRAGMENT SIZE DISTRIBUTION PATTERN OF AMNIOTIC FLUID CELL-FREE FETAL DNA FOR PRENATAL DIAGNOSIS
FRAGMENT SIZE DISTRIBUTION PATTERN OF AMNIOTIC FLUID CELL-FREE FETAL DNA FOR PRENATAL DIAGNOSIS
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机译:羊水无胎儿胎儿DNA片段大小分布模式的产前诊断
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摘要
The present invention relates to improved methods of prenatal diagnosis, screening, monitoring and/or testing. The inventive methods include analysis of the fragment size distribution of cell-free fetal DNA isolated from amniotic fluid. The inventive methods allow for rapid screening of fetal characteristics such as chromosomal abnormalities and for prenatal diagnosis of a variety of diseases and conditions. Since the new methods do not require cell culture, they can be performed more rapidly than conventional fetal karyotypes.
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