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Chip-based speciation and phenotypic characterization of microorganisms

机译:基于芯片的物种形成和微生物的表型表征

摘要

This invention relates to a method for identifying a genotype of a first organism, comprising:(a) providing an array of oligonucleotides at known locations on a substrate, said array comprising probes complementary to reference DNA or RNA sequences from a second organism;(b) hybridizing a target nucleic acid sequence from the first organism to the array; and(c) based on an overall hybridization pattern of the target to the array, identifying the genotype of the first organism, and optionally identifying a phenotype of the first organism.
机译:本发明涉及一种鉴定第一生物的基因型的方法,包括:(a)在底物上的已知位置处提供寡核苷酸阵列,所述阵列包含与来自第二生物的参考DNA或RNA序列互补的探针;(b)使来自第一生物的靶核酸序列与阵列杂交;和(c)基于靶标与阵列的总体杂交模式,鉴定第一生物的基因型,以及任选地鉴定第一生物的表型。

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