One embodiment is a method including creating a protein interaction network including a plurality of protein IDs and a plurality of interactions between protein IDs, determining confidences of interactions of the protein interaction network, identifying a sub-network of the protein interaction network, and determining relevance of proteins of the sub-network to a biological process. Other embodiments include unique systems and methods relating to mining protein interaction networks. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the following descriptions, drawings, and claims.
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