INJECTABLE THERMOSENSITIVE PLURONIC HYDROGELS COUPLED WITH BIOACTIVE MATERIALS FOR TISSUE REGENERATION AND PREPARATION MEHTOD THEREOF

摘要

An injectable thermosensitive pluronic derivative hydrogel coupled with a biologically active material such as a ligand peptide having a cell affinity or a growth factor for tissue regeneration, and a preparation method thereof, comprising: coupling a pluronic derivative with methacryloxyethyltritrimellitic anhydride having a double bond and a functional group; and introducing a ligand peptide having a cell affinity or a growth factor to the resultant.