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A MATERIAL WITH BLOOD COMPATIBILITY AND PREPARATION METHOD THEREOF

机译:具有血液相容性的材料及其制备方法

摘要

A method of preparing a material with blood compatibility comprises dissolving polymer into an organic solvent to form a polymer solution; dissolving an anticoagulant in an inorganic solvent to form an emulsion, slurry or fluid-like mixture; then producing the material with blood compatibility by one of the following means:1) mixing the polymer solution and the emulsion, slurry or fluid-like mixture containing the anticoagulant to make the material with blood compatibility; 2) mixing the polymer solution, a pore forming agent and the emulsion, slurry or fluid-like mixture containing the anticoagulant to make the material with blood compatibility; 3) mixing the polymer solution, a filler and the emulsion, slurry or fluid-like mixture containing the anticoagulant to make the material with blood compatibility. And a material with blood compatibility is prepared by said method. The material has good anticoagulant property, and can meet the requirements of various properties as tissue and organ repair material used in vitro or implanted in vivo such as good anticoagulant property, biocompatibility, high mechanical strength, toughness and the like.
机译:一种具有血液相容性的材料的制备方法,包括将聚合物溶解在有机溶剂中形成聚合物溶液。将抗凝剂溶解在无机溶剂中以形成乳液,浆液或流体状混合物;然后通过以下方式之一制备具有血液相容性的材料:1)将聚合物溶液与包含抗凝剂的乳液,浆液或流体状混合物混合以使该材料具有血液相容性; 2)将聚合物溶液,成孔剂与包含抗凝剂的乳液,浆液或流体状混合物混合,以使材料具有血液相容性; 3)将聚合物溶液,填料和包含抗凝剂的乳液,浆液或流体状混合物混合,以使该材料具有血液相容性。然后通过上述方法制备具有血液相容性的材料。该材料具有良好的抗凝性能,并可以满足体外或体内植入的组织和器官修复材料的各种性能要求,例如良好的抗凝性能,生物相容性,较高的机械强度,韧性等。

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