SINGLE-USE MANIFOLD FOR AUTOMATED, ASEPTIC TRANSFER OF SOLUTIONSPIN BIOPROCESSING APPLICATIONS COMPRISING AT LEAST ONE CONDUCTIVITY SENSOR APPLICATIONS

摘要

Presteralized manifolds are provided which are designed for sterile packaging and single-use approaches. Disposable tubing and flexible-wall containers are assembled via aseptic connectors. These manifolds interact with valves and pumping equipment which can be operated by a controller which provides automated and accurate delivery of biotechnology fluid. The manifold also being used in conjunction with one or more conductivity sensors used to measure the conductivity of the biotechnology fluid. Such sensors interact with the controller or are connected to a separate user interface. The combination of disposable tubing, flexible-wall containers, aseptic connectors, manifold, controller, and conductivity sensors provides an aseptic environment while avoiding or reducing cleaning and quality assurance procedures.