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SEROLOGICAL METHOD FOR DETECTING INTESTINAL MICROVILLI ATROPHY IN PATIENTS SUFFERING FROM COELIAC DISEASE
SEROLOGICAL METHOD FOR DETECTING INTESTINAL MICROVILLI ATROPHY IN PATIENTS SUFFERING FROM COELIAC DISEASE
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机译:血清学方法检测小肠疾病患者肠道微绒毛萎缩
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摘要
Method for detecting intestinal microvilli atrophy in a patient suffering from coeliac disease including immunological detection of anti F-actin autoantibodies in a biological fluid from the patient consisting of the following steps: a) preparation of a normal epithelial cell culture from small bowel of experimental animal; b) incubation with the patient fluid; c) detection of the binding of anti F-actin autoantibodies to the cells. Further said method can include, following step a) the incubation with a substance able to induce the polymerisation of globular actin to filaments.
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