ENHANCEMENT OF IN VITRO CULTURE OR VACCINE PRODUCTION IN BIOREACTORS USING ELECTROMAGNETIC ENERGY

摘要

Disclosed are apparatus and methods for enhancing or improving cell cultures, including cell cultures for the production of monoclonal antibodies, using electromagnetic energy treatment, primarily using electromagnetic radiation in the near infrared to visible region of the spectrum. The delivery of electromagnetic energy to a culture, in accordance with preferred embodiments, enhances or improves the cell culture such as by providing for enhanced and accelerated formation of important biological macromolecules, including, but not limited to, antibodies, proteins, collagen, and polysaccharides, and also providing for accelerated cellular replication and an enhancement or prolongation of the life of cells so treated. The electromagnetic radiation deliveres to the culture has a power density of at least 1 mw/cm2 within a wavelength bandwidth of less than or equal to 100 nanometers.