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SOLID ORAL DOSAGE FORMS OF GRISEOFULVIN

机译:固豆氟醚的固体口服剂型

摘要

A taste masked solid oral discrete dosage form comprising griseofulvin, a pharmaceutical composition comprising the same and a process for the preparation thereof . The taste masked solid oral discrete dosage forms comprises a core and/or one or more coating layers The pharmaceutical suspension composition is in the form of taste masked pellets comprising griseofulvin and one or more coating layers. The process of preparation of the taste masked solid oral discrete dosage forms comprising griseofulvin, comprises the steps of reducing the particle size of griseofulvin, blending with the other excipients, granulation, extrusion- spheronization, drying and screening to obtain discrete dosage forms, said discrete dosage forms are further coated with one or more film coating layers to achieve taste masking.
机译:包含灰黄霉素的掩味固体口服离散剂型,包含其的药物组合物及其制备方法。掩味的固体口服离散剂型包含核心和/或一个或多个包衣层。药物悬浮液组合物为掩味的小丸形式,其包含灰黄霉素和一个或多个包衣层。制备包含灰黄霉素的掩味固体口服离散剂型的方法包括以下步骤:减小灰黄霉素的粒度,与其他赋形剂混合,制粒,挤出滚圆,干燥和筛选以获得离散剂型,所述离散剂剂型进一步用一个或多个薄膜包衣层包衣以掩味。

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