首页> 外国专利> SYSTEM AND METHOD FOR PROVIDING CELL SPECIFIC LASER THERAPY OF ATHEROSCLEROTIC PLAQUES BY TARGETING LIGHT ABSORBERS IN MACROPHAGES

SYSTEM AND METHOD FOR PROVIDING CELL SPECIFIC LASER THERAPY OF ATHEROSCLEROTIC PLAQUES BY TARGETING LIGHT ABSORBERS IN MACROPHAGES

机译:通过定位巨噬细胞中的光吸收剂来提供动脉粥样硬化斑块的细胞特定激光治疗的系统和方法

摘要

An apparatus and method according to the present invention can be provided, e.g., for a cell specific laser therapy of atherosclerotic plaques, particularly to systems and methods for targeting endogenous light absorbers present within plaque macrophages and exogenous nanoparticle targeting. In one exemplary embodiment, an electro-magnetic radiation can be forwarded to an anatomical structure. The electro-magnetic radiation may have at least one property configured to (a) modify at least one characteristic of at least one first cell, and (b) minimize any modification of and/or modify at least one characteristic of at least second cell. The first and second cells may be different from one another, the characteristics of the first and second cells can be different from one another, and the first cell and/or the second cell may have at least one macrophage feature, and the characteristic of the at least one first cell and/or the at least one second cell can be temperature. According to still another exemplary embodiment, a location associated with the first cell and the second cell can be determined. For example, the electro-magnetic radiation can be forwarded in a vicinity of the location.
机译:可以提供根据本发明的设备和方法,例如,用于动脉粥样硬化斑块的细胞特异性激光治疗,特别是用于靶向斑块巨噬细胞内存在的内源性光吸收剂和外源性纳米颗粒靶向的系统和方法。在一个示例性实施例中,电磁辐射可以被转发到解剖结构。电磁辐射可以具有被配置为(a)改变至少一个第一电池的至少一个特性,以及(b)最小化对至少第二电池的至少一个特性的修改和/或改变其至少一个特性的至少一个特性。第一细胞和第二细胞可以彼此不同,第一细胞和第二细胞的特征可以彼此不同,并且第一细胞和/或第二细胞可以具有至少一个巨噬细胞特征,并且至少一个第一电池和/或至少一个第二电池可以是温度。根据又一示例性实施例,可以确定与第一小区和第二小区相关联的位置。例如,电磁辐射可以在该位置附近转发。

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