BIOAVAILABILITY ENHANCEMENT OF LIPOPHILIC DRUG BY USE SOLVENT SYSTEM

摘要

Compositions and methods for improving the efficacy and/or transdermal transport of topically administered pharmacologically active compounds are disclosed. Preferably, the pharmacologically active compound is incorporated in a carrier comprising an effective amount of a lipophilic pharmaceutically acceptable compound selected from the group consisting of alcohol, glycols, ethers and mixtures thereof, most preferably benzyl alcohol. In certain embodiments, compositions and methods of treatment for anti-fungal compositions are disclosed that exhibit enhanced permeation. In another embodiment and improved, stable topical composition of prostaglandin is disclosed.