PEPTIDES DERIVED FROM DECORIN LEUCINE RICH REPEATS AND USES THEREOF

摘要

A first aspect of the invention provides a peptide consisting of from 5 to 40 amino acids from the portion of decorin which contains the leucine-rich repeats (LRRs), or a variant of said peptide. A second aspect of the invention provides a peptide consisting of no more than 250 amino acid residues comprising two or more peptides of the first aspect of the invention, or a peptide of the first aspect of the invention and additional peptide sequence not derived from decorin, or a variant of said peptide of no more than 250 amino acid residues. The peptides of the invention may be used for inhibiting undesirable angiogenesis, for example in the treatment of cancer.