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METHOD OF PASSIVE IMMUNIZATION AGAINST DISEASE OR DISORDER CHARACTERIZED BY AMYLOID AGGREGATION WITH DIMINISHED RISK OF NEUROINFLAMMATION
METHOD OF PASSIVE IMMUNIZATION AGAINST DISEASE OR DISORDER CHARACTERIZED BY AMYLOID AGGREGATION WITH DIMINISHED RISK OF NEUROINFLAMMATION
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机译:消除因淀粉样蛋白凝集而引起疾病或神经紊乱的被动免疫方法
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Unglycosylated anti-amyloid antibodies maintained all the antigen recognition functions of the native glycosylated anti-amyloid antibodies but without, or with a much reduced, property of triggering Fc receptor-mediated inflammation response in the brain. Such unglycosylated antibodies can be used in a method for preventing, inhibiting, or treating a disease or disorder characterized by amyloid aggregation with a diminished risk of triggering or exacerbating neuroinflammation.
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