COMPOSITION FOR CELL THERAPY OF AMYOTROPHIC LATERAL SCLEROSIS USING MANNITOL AND STEM CELL DERIVED FROM UMBILICAL CORD BLOOD

摘要

A composition comprising mannitol and a stem cell derived from umbilical cord blood is provided to be able to fundamentally treat patients suffering from amyotrophic lateral sclerosis, about which there are no surgical or medicinal treating methods. The composition for treating a patient suffering from amyotrophic lateral sclerosis comprises a stem cell derived from umbilical cord blood which is obtained by adding an anti-coagulating agent to pure umbilical cord blood having more than 45 ml per 1 unit within 24 hours of delivery, diluting the anti-coagulating agent mixed umbilical cord blood with alpha-minimum essential medium(alphaMEM) and then centrifuging it to obtain monocyte therefrom, and then float-culturing the obtained monocyte in the alphaMEM containing stem cell factor, granulocyte-macrophage colony-stimulating factor(GM-CSF), granulocyte colony-stimulating factor(G-CSF), interleukin-3(IL-3) and IL-6.