Method for preparing optically active R-2-chloromandelic acid and its ester derivatives using Baker's Yeast

摘要

The present invention yeast (Baker's Yeast) using optically active (R) -2- chloro only psychedelic acid ((R) -2-chloromandelic acid) , and relates to a manufacturing method of an ester derivative , more specifically, an alkyl phosphate buffer solution under the presence of 2-chloro -benzoyl formate (Alkyl 2-Chloro-benzoylformate) a yeast ( Baker's yeast) optionally an optically active (R) -2-chloro only by biological method of reducing by using a method for producing the psychedelic acid and its ester derivatives . The production method of the present invention is highly price is inexpensive and easy to use yeast to obtain a manufacturing process is simple and economical , the optical purity and high yield is very useful industrially .