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FUSION PROTEINS AND METHODS FOR DETERMINING PROTEIN-PROTEIN-INTERACTIONS IN LIVING CELLS AND CELL LYSATES, NUCLEIC ACIDS ENCODING THESE FUSION PROTEINS, AS WELL AS VECTORS AND KITS CONTAINING THESE
FUSION PROTEINS AND METHODS FOR DETERMINING PROTEIN-PROTEIN-INTERACTIONS IN LIVING CELLS AND CELL LYSATES, NUCLEIC ACIDS ENCODING THESE FUSION PROTEINS, AS WELL AS VECTORS AND KITS CONTAINING THESE
The present invention refers to inventive fusion proteins, to a method for detecting protein-protein-interactions in living cells and cell lysates using these inventive fusion proteins. The present invention also refers to a screening method for identifying compounds suitable to modify, i.e. inhibit or enhance, protein-protein-interaction using these fusion porteins. Additionally a method for detecting cells is disclosed comprising an unknown protein that interacts with a known protein. Along with the inventive fusion proteins used for these methods encoding nucleic acids, corresponding vectors and host cells transfected accordingly are disclosed herewith.
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