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Novel Hydrate Forms of Alendronate Sodium, Methods for Making the Same, and Pharmaceutical Compositions thereof
Novel Hydrate Forms of Alendronate Sodium, Methods for Making the Same, and Pharmaceutical Compositions thereof
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机译:阿仑膦酸钠的新型水合物形式,其制备方法及其药物组合物
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摘要
New hydrate forms of alendronate sodium, having water content of between about one and about twelve percent, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium B, D, E, F, G and H, and processes for manufacturing them, are also disclosed. These new forms of alendronate sodium are suitable for incorporation into pharmaceutical compositions for combating bone resorption in bone diseases.
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