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Single nucleotide polymorphism marker of XPG allele for the diagnosis of lung cancer risk
Single nucleotide polymorphism marker of XPG allele for the diagnosis of lung cancer risk
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机译:XPG等位基因的单核苷酸多态性标志物诊断肺癌风险
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摘要
The present invention relates to an XPG polymorphism marker for diagnosing lung cancer and a method for diagnosing lung cancer using the same. More specifically, the 3507 th nucleotide sequence of the XPG gene described in SEQ ID NO: 4 is C / Polymorphic marker for diagnosing risk for lung cancer, characterized in that it comprises 50 to 300 nucleotide sequences comprising a genotype consisting of C, C / G and G / G and methods for diagnosing the risk for lung cancer using the same It is about. The C3507G polymorphism in the XPG gene of the present invention can be usefully used as a genetic marker useful for diagnosing the genetic susceptibility of lung cancer specifically. By using this, the genetic susceptibility of lung cancer can be diagnosed.
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机译:本发明涉及一种用于诊断肺癌的XPG多态性标志物以及使用该标志物诊断肺癌的方法。更具体地,SEQ ID NO:4中描述的XPG基因的第3507个核苷酸序列是用于诊断肺癌风险的C /多态性标记,其特征在于它包含50至300个核苷酸序列,该核苷酸序列包含由C,C / G和G / G以及使用相同的诊断肺癌风险的方法。本发明的XPG基因中的C3507G多态性可以用作有用的遗传标记,用于特异性地诊断肺癌的遗传易感性。通过使用该方法,可以诊断肺癌的遗传易感性。
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