METHOD FOR PRODUCING biologically active substances, biologically active substances and aqueous extract of placenta

摘要

1. method u043fu043eu043bu0443u0447u0435u043du0438u00a0 biologically active substance, which comprises a mechanical grinding and homogenization of the pig placenta extract, a water u0433u043eu043cu043eu0433 u0435u043du0438u0437u0430u0442u0430 and conservation of u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0, aqueous extract u0433u043eu043cu043eu0433u0435u043du0438u0437u0430u0442u0430 produced by his u0440u0430u0437u0431u0430u0432u043bu0435u043du0438u00a0 distilled water in a ratio of 0.8 - 1.2 mas. h. water for 1 hour.u0433u043eu043cu043eu0433u0435u043du0438u0437u0430u0442u0430, water slurry u0433u043eu043cu043eu0433u0435u043du0438u0437u0430u0442u0430 u043eu0431u0435u0441u0446u0432u0435u0447u0438u0432u0430u044eu0442 addition to the suspension of 0.006 - 0007 mas. h.citric acid, and at u043fu0440u043eu0442u00a0u0436u0435u043du0438u0438 70 - 110 min in u043fu0435u0440u0435u043cu0435u0448u0438u0432u0430u043du0438u0438, then stand on the u043fu0440u043eu0442u00a0u0436u0435u043du0438u0438 10 to 20 min, u0434u0435u043au0430u043du0442u0438u0440u0443u044eu0442, conservation u043eu0441u0443u0449u0435u0441u0442u0432u043bu00a0u044eu0442 by u0434u043eu0431u0430u0432u043b u0435u043du0438u00a0 to u0441u0443u043fu0435u0440u043du0430u0442u0430u043du0442u0443 u043du0438u043fu0430u0433u0438u043du0430, supernatant with preservatives have to u043fu0440u043eu0442u00a0u0436u0435u043du0438u0438 45 to 75 min, after which the particles with the size of the u0434u0435u043au0430u043du0442u0438u0440u043eu0432u0430u043du043du043eu0433u043e u0441u0443u043fu0435u0440u043du0430u0442u0430u043du0442u0430 u0443u0434u0430u043bu00a0u044eu0442 mi more than 3 microns by filtration.;2. method for u043eu0442u043bu0438u0447u0430u0435u0442u0441u00a0 1, so that as the additive to the u0441u0443u043fu0435u0440u043du0430u0442u0430u043du0442u0443 u0434u043eu0431u0430u0432u043bu00a0u044eu0442 u043du0438u043fu0430u0433u0438u043d in amounts of 0.1 - 0.3 weight%.;3. method for u043eu0442u043bu0438u0447u0430u0435u0442u0441u00a0 2, so that u043du0438u043fu0430u0433u0438u043d u0434u043eu0431u0430u0432u043bu00a0u044eu0442 in the form of a 5% solution in u043fu0440u043eu043fu0438u043bu0435u043du0433u043bu0438u043au043eu043bu0435.;4. biologically active substance, the method for 1 or 2, which includes the free amino acids, peptides and u043du0438u0437u043au043eu043cu043eu043bu0435u043au0443u043bu00a0u0440u043du044bu0435 organic residue in sl u0435u0434u0443u044eu0449u0435u043c% of the dry weight ratio of the components.;free amino acids from 100 to 500 u043421,6 - 26,6u043fu0435u043fu0442u0438u0434u044b from 1000 to 2000 u043435,3 - 43,1u043fu0435u043fu0442u0438u0434u044b from 3000 to 5000 u043416,5 - 20,1u043du0438u0437u043au043eu043cu043eu043bu0435u043au0443u043bu00a0u0440u043du044bu0435u043eu0440u0433u0430u043du0438u0447u0435u0441u043au0438u0435 balances of less than 100 u0434u043eu0441u0442u0430u043bu044cu043du043eu0435;5. the aqueous extract of placenta pigs, including the water fraction of peptides and free amino acids of the pig placenta, u043du0438u043fu0430u0433u0438u043d, propylene glycol and u043eu0431u0435u0441u0446u0432u0435u0447u0438u0432u0430u044eu0449u0435u0435 ve society as auxiliary substances, u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0 that contains biologically active substance on p.4 comprising the water fraction of peptides and free amino acids in the placental tissue of pigs, the weight ratio of the components.%.;biologically active u0432u0435u0449u0435u0441u0442u0432u043e0,1 - 0,35u043du0438u043fu0430u0433u0438u043d0,18 - 0,22u043eu0431u0435u0441u0446u0432u0435u0447u0438u0432u0430u044eu0449u0435u0435 u0432u0435u0449u0435u0441u0442u0432u043e0,3 - 0,4u043fu0440u043eu043fu0438u043bu0435u043du0433u043bu0438u043au043eu043bu044c2,5 - 6,0u0432u043eu0434u0430u043eu0441u0442u0430u043bu044cu043du043eu0435;6. the aqueous extract on clause 5, u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0, as u043eu0431u0435u0441u0446u0432u0435u0447u0438u0432u0430u044eu0449u0435u0433u043e substance contains citric acid.