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PREPARATION COMPRISING INHIBITOR OF HETEROTRIMERIC G PROTEINS SIGNAL TRANSDUCTION IN COMBINATION WITH OTHER CYTOSTATIC AGENT FOR THERAPEUTIC USING IN CANCER TREATMENT
PREPARATION COMPRISING INHIBITOR OF HETEROTRIMERIC G PROTEINS SIGNAL TRANSDUCTION IN COMBINATION WITH OTHER CYTOSTATIC AGENT FOR THERAPEUTIC USING IN CANCER TREATMENT
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机译：包含异三聚体G蛋白信号转导抑制剂与其他细胞抑制剂联合用于癌症治疗的抑制剂的制备
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摘要
FIELD: medicine, oncology, pharmacology, pharmacy.;SUBSTANCE: invention relates to a preparation used in the simultaneous, separate or time-distributed therapeutic using in cancer treatment. The preparation comprises inhibitor of signals transduction of heterotrimeric G proteins chosen from 7-(2-amino-1-oxo-3-thiopropyl)-8-(cyclohexylmethyl)-2-methylphenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine, 7-(2-amino-1-oxo-3-thiopropyl)-8-(cyclohexylmethyl)-2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine and at least one additional cytostatic agent also. Proposed preparations possess the enhanced effectiveness.;EFFECT: enhanced and valuable medicinal properties of preparation.;6 cl, 5 tbl, 1 ex
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机译：技术领域本发明涉及用于癌症治疗的同时，分开或按时间分布的治疗剂的制剂。该制剂包含选自7-（2-氨基-1-氧代-3-硫丙基）-8-（环己基甲基）-2-甲基苯基-5,6,7,8-四氢咪唑的异三聚体G蛋白的信号转导抑制剂[1] ，2-a]吡嗪，7-（2-氨基-1-氧代-3-硫丙基）-8-（环己基甲基）-2-苯基-5,6,7,8-四氢咪唑并[1,2-a]吡嗪以及至少一种其他的细胞抑制剂。拟议的制剂具有增强的功效。效果：制剂的增强的和有价值的药用特性。6cl，5 tbl，1 ex
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