EMETINE HYDROCHLORIDE GRANULATE, METHOD FOR ITS PREPARING AND MEDICINAL FORMULATION BASED ON THEREOF

摘要

FIELD: medicine, pharmacology, pharmacy.;SUBSTANCE: invention relates to a novel granulated formulaton of emetine hydrochloride used in prophylaxis and treatment of alcoholism. The formulation comprises 70-90% of emetine hydrochloride, polyvinylpyrrolidone and eudragite, a tabletted or capsulated medicinal formulation based on thereof. Also, invention relates to a method for preparing the indicated granulate. Invention provides delivery of emetine hydrochloride in intestine and suppression of the emetic effect.;EFFECT: improved preparing method, valuable medicinal properties of granulate.;4 cl, 6 tbl, 32 ex