New human antibody that is able to bind human CD152 or its antibody fragment, useful for treating tumor disease e.g. lung cancer, skin cancer, bone cancer, uterus cancer, ovarian cancer and stomach cancer

摘要

A human antibody that is able to bind human CD152 (cytotoxic T lymphocyte antigen (CTLA)-4) or its antibody fragment, where a heavy chain (VH3) and a light chain (V lambda ) of the antibody derived from the human germ line, is new. An independent claim is included for a pharmaceutical composition comprising a human antibody. ACTIVITY : Cytostatic. No biological data given. MECHANISM OF ACTION : CD152 inhibitor.