use of depsipeptide and its analogue as immunosuppressiva for treatment of infectious diseases, autoimmune diseases, allergies and hyperproliferativer skin diseases

摘要

Depsipeptides and congeners thereof are disclosed having structure (I), wherein m, n, p, q, X, R1, R2 and R3 are as defined herein. These compounds, including FR901228, have activity as immunosuppressants for treating an infections disease, an autoimmune disease, allergic reactions or a hyperproliferative skin disease.