A process for preparing a recombinant yeast s. cerevisiae by the use of essential and regulatory genes of mycobacteria

摘要

The present invention relates to an in vivo drug screening method taking advantage of the yeast two-hybrid system provides a method of using the whiB genes which are regulatory genes of mycobacteria, whose functions have not been reported so far, as drug target by using the yeast Saccharomyces cerevisiae as a surrogate host.