USE OF 11BETA- (4-ACETYLPHENYL) -17BETA-HYDROXY-17ALPHA- (1,1,2,2-PENTAFLUOROETHYL) ESTRA-4,9-DIEN-3-ON FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF BREAST, EGGSTICK, , ENDOMETRIC CANCER, MYELOMA AND MENINGIOM

摘要

The present invention relates to methods and uses for inducing apoptosis in a cell, in particular a breast cancer cell, by the administration of antiprogestins, in particular the antiprogestin 11 beta -(4-acetylphenyl)-17 beta -hydroxy-17 alpha -(1,1,2,2,2-pentaf luoroeth yl)-estra-4,9-dien-3-one or a pharmaceutically acceptab le derivative or analogue thereof. The invention further relates to a treatment of cancer wherein an indicator of high risk is an increased amount of tumor cells in the S-phase of the cell cycle, said treatment comprising an antiprogestin, in particular the antiprogestin 11 beta -(4-acetylphenyl)-17 beta -hydroxy-17 alpha -(1, 1,2, 2,2- pentafluoroethyl)-estra-4,9-dien-3-one or a pharmaceutically acceptable derivative or analogue thereof.