nitrooxyderivate of fluvastatin, pravastatin, atorvastatin, cerivastatin, and rosuvastatin as cholesterol lowering means with improved antiphlogistischer, antithrombotischer and thrombozytenaggregationshemmender effect

摘要

Statin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular coronary syndromes, neurodegenerative disorders as well as for reducing cholesterol levels.