method for the diagnosis of kolorektaladenomen and cancer with protonenmagnetresonanzspektroskopie

摘要

One dimensional proton magnetic resonance spectroscopy of human stool can be used as non-invasive method of detecting the presence of colorectal cancer and/or clinically significant adenomas. A stool sample is mixed with a buffer to form a suspension, the suspension is centrifuged to yield a supernatant sample, which is subjected to magnetic resonance spectroscopy, and the resulting spectrum is compared with that of stool from non-cancerous subjects, observed differences in spectra being indicative of cancer and/or clinically significant adenomas.