首页> 外国专利> Injection system for the application of semi-solid, depot-shaped pharmaceutical compositions of gellable peptide salts

Injection system for the application of semi-solid, depot-shaped pharmaceutical compositions of gellable peptide salts

机译:注射系统,用于胶凝肽盐半固体,长效型药物组合物的应用

摘要

The invention features a solid, non-particulate, sustained-release pharmaceutical composition for parenteral administration to a patient. The composition consists essentially of (1) a soluble, gelable peptide salt, and (2) up to 30 percent, by weight, of a pharmaceutically acceptable, monomeric, soluble carrier, compounded into a solid cylindrical form, wherein the solid composition automatically forms a gel after interaction with the patient's bodily fluids, the gel releasing the peptide continuously within the patient over an extended period of at least three days.
机译:本发明的特征在于用于肠胃外给予患者的固体,非颗粒,持续释放的药物组合物。所述组合物基本上由(1)可溶的可胶凝的肽盐和(2)按重量计高达30%的可药用的单体可溶的载体混合成固体圆柱形形式组成,其中所述固体组合物自动形成在与患者体液相互作用后形成凝胶,该凝胶在至少三天的延长时间内在患者体内连续释放肽。

著录项

  • 公开/公告号DE69535322D1

    专利类型

  • 公开/公告日2007-01-11

    原文格式PDF

  • 申请/专利号DE19956035322T

  • 发明设计人 CHERIF-CHEIKH ROLAND;

    申请日1995-08-31

  • 分类号A61M5/28;A61J1;A61J1/20;A61K9;A61K9/06;A61K9/10;A61K9/16;A61K9/19;A61K9/20;A61K9/70;A61K38;A61K38/04;A61K38/09;A61K38/16;A61K38/22;A61K38/23;A61K38/25;A61K38/28;A61K38/29;A61K38/31;A61K47;A61K47/26;A61K47/36;A61M5/142;A61M5/178;A61M5/31;A61M5/315;A61M31;

  • 国家 DE

  • 入库时间 2022-08-21 20:27:33

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