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Methods for identifying compounds capable of modulating CFTR/C2 interaction and/or CFTR phosphorylation by CK2
Methods for identifying compounds capable of modulating CFTR/C2 interaction and/or CFTR phosphorylation by CK2
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机译:鉴定能够通过CK2调节CFTR / C2相互作用和/或CFTR磷酸化的化合物的方法
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摘要
A method of identifying a compound capable of modulating CFTR/CK2 interaction and/or CFTR phosphorylation by CK2 comprising exposing CFTR and/or CK2 to a test compound and assessing the effect of the test compound on CFTR/CK2 interaction and/or CFTR phosphorylation by CK2. A method of screening for compounds of use in preventing or treating a secretory state or disorder and/or a cancer and/or cystic fibrosis wherein CFTR and/or CK2 is exposed to a test compound and the effect of the test compound on CFTR/CK2 interaction and/or CFTR phosphorylation by CK2 is assessed.
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