CATALYST FOR COUPLING AND LIGAND USED FOR THE SAME AND METHOD FOR PRODUCING COMPOUND HAVING BIARYL STRUCTURE BY CROSS COUPLING REACTION

摘要

PROBLEM TO BE SOLVED: To provide a new phosphine compound for a ligand of a catalyst useful for cross coupling reaction and its metal complex.;SOLUTION: The phosphine compound is represented by formula (I) (R¹ and R² are each a cycloalkyl group or the like; n is 1-3 and m is an integer of 1 or 2). A Pd metal complex comprises the phosphine compound as a ligand. In a method for producing a compound having a biaryl structure by carrying out cross coupling of an aromatic compound with a Grignard reagent, the reaction is carried out in the presence of the metal complex.;COPYRIGHT: (C)2009,JPO&INPIT