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MICRO RNA TARGET GENE PREDICTING DEVICE, MICRO RNA TARGET GENE PREDICTING METHOD, AND PROGRAM

机译:微小RNA目标基因的预​​测装置,微小RNA目标基因的预​​测方法和程序

摘要

PPROBLEM TO BE SOLVED: To provide a device, method and program capable of obtaining a prediction result of a sufficiently narrowed down target gene by excluding a large amount of pseudo-positive prediction results and predicting a target gene about a micro RNA transcriptional product resolution function. PSOLUTION: A gene to be a micro RNA target is predicted on the basis of alignment, genes having the prescribed number of a plurality of target sites or more are extracted, genes whose micro RNA-gene correlation coefficient is not higher than a prescribed negative number are extracted, a set intersection of the genes extracted on the basis of the number of target sites and the genes extracted on the basis of the correlation coefficient is calculated, a combination of two genes is selected as a pair from the set intersection, a likelihood that there is a relation between the correlation or a cooccurrence relation of a gene pair and a matter that the gene pair makes micro RNA common is examined with respect to the selected gene pair, and the gene pair is extracted based on the likelihood. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:提供一种装置,方法和程序,该装置,方法和程序能够通过排除大量的假阳性预测结果并预测关于微小RNA转录的靶基因来获得足够缩小的靶基因的预测结果。产品解析功能。

解决方案:基于比对预测作为微小RNA靶标的基因,提取具有指定数目的多个靶位点或更多的靶标的基因,其微小RNA-基因相关系数不高于提取指定的负数,根据目标位点的数目提取基因的设定交点,并计算基于相关系数提取的基因,从设定的交点中选择两个基因的组合作为一对然后,针对选择的基因对检查基因对的相关性或共现关系之间的相关性与该基因对使微小RNA通用的问题之间的可能性,并基于该可能性来提取基因对。 。

版权:(C)2009,日本特许厅&INPIT

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