首页> 外国专利> SUPPRESSANT OF CELL DEATH DERIVED FROM ENDOPLASMIC RETICULUM STRESS OR OXIDATION STRESS

SUPPRESSANT OF CELL DEATH DERIVED FROM ENDOPLASMIC RETICULUM STRESS OR OXIDATION STRESS

机译:内质网应激或氧化应激引起的细胞死亡抑制剂

摘要

PPROBLEM TO BE SOLVED: To provide a pharmaceutical composition useful for suppressing cell death derived from endoplasmic reticulum stress and/or cell death derived from oxidation stress. PSOLUTION: A suppressant of cell death derived from endoplasmic reticulum stress and cell death derived from oxidation stress, containing a carbazole derivative represented by general formula (I) (wherein, RSP1/SPis H or a 1-6C alkoxy; and RSP2/SP, RSP3/SPand RSP4/SPare each H, a halogen, a 1-6C alkyl, a 1-6C alkyl halide, cyano or the like) or a pharmaceutically permissible salt thereof as an active ingredient, is provided. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:<要解决的问题:提供一种药物组合物,其可用于抑制源自内质网应激的细胞死亡和/或源自氧化应激的细胞死亡。

解决方案:一种抑制内质网应激的细胞死亡和氧化应激的细胞死亡的抑制剂,其中含有通式(I)表示的咔唑衍生物(其中R 1 为H或a 1-6C烷氧基;和R 2 ,R 3 和R 4 分别为H,卤素,1-6C烷基,1提供了作为活性成分的-6C烷基卤化物,氰基等或其药学上允许的盐。

版权:(C)2009,日本特许厅&INPIT

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