MEDICINE CARRIER FOR DRUG DELIVERY SYSTEM, SOLUBILIZER FOR MEDICINE AND COMPOUND AND USING THE SAME, AND COMPOSITION CONTAINING THE SOLUBILIZER

摘要

PPROBLEM TO BE SOLVED: To settle the problems wherein poorly water-soluble materials are, even if the materials have pharmacological activity, practically hardly administered in vivo and selection of medicinal materials is reduced, virus type carriers have fear of toxicity removal as a carrier transferring these medicines even if the carriers have in vivo carrying ability, and artificially synthesized materials are absorbed in vivo or remains without excreted outside the body. PSOLUTION: A lipocalin family, which is a bioproduct, has a barrel shape structure inside comprising hydrophobic group and can take in hydrophobic materials to carry. So the lipocalin family is bonded with a poorly water-soluble medicine, to be used as a medicine carrier of a DDS system. As the lipocalin family also can improve solubility of materials so can be used as a solubilizer. PCOPYRIGHT: (C)2008,JPO&INPIT