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Treatment, prevention, and amelioration of pulmonary diseases associated with chemotherapy or radiation therapy with active vitamin D compounds or mimetics thereof

机译:用活性维生素D化合物或其模拟物治疗,预防和改善与化学疗法或放射疗法有关的肺部疾病

摘要

The present invention relates to a method for preventing, treating or ameliorating pulmonary disorders in a patient receiving a chemotherapeutic or radiotherapeutic agent or treatment comprising administering to the patient a pharmaceutical composition comprising an effective amount of active vitamin D compound or a mimic thereof. According to the invention, the active vitamin D compound, or the mimic thereof, may be administered by HDPA so that high doses of the active vitamin D compound can be administered to an animal without inducing severe symptomatic hypercalcemia.
机译:本发明涉及在接受化学治疗或放射治疗剂或治疗的患者中预防,治疗或改善肺部疾病的方法,该方法包括向患者施用包含有效量的活性维生素D化合物或其模拟物的药物组合物。根据本发明,可以通过HDPA施用活性维生素D化合物或其模拟物,从而可以将高剂量的活性维生素D化合物施用给动物而不会引起严重的症状性高钙血症。

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