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Method for measuring complete parathyroid hormone and method for identifying bone condition in patients with parathyroid disease and chronic renal failure
Method for measuring complete parathyroid hormone and method for identifying bone condition in patients with parathyroid disease and chronic renal failure
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机译:甲状旁腺疾病和慢性肾功能衰竭患者全甲状旁腺激素的测定方法和骨状况的鉴定方法
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摘要
The present invention relates to novel methods and devices for differentiating in a patient parathyroid diseases, such as hyperparathyroidism and related bone diseases, from normal or non-disease states. One detects whole or non-fragmented (1 to 84) parathyroid hormone in a biological sample and also a large non-whole parathyroid hormone peptide fragment that can function as a parathyroid hormone antagonist. By either comparing values or using independently the value of either the large non-whole parathyroid hormone peptide fragment, the whole parathyroid hormone, or the combination of these values one is able to differentiate parathyroid and bone related disease states, as well as differentiate such states from normal states.
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