Site-specific immunization method for constructing an antibody having specificity for the E7 oncoprotein of high-risk HPV types

摘要

And due to the fact that together with the region having a similar high to E7 proteins of low-risk HPV, to remove a motif that is evolutionarily conserved, as compared to when immunized with whole antigen of high-risk HPV, the present invention, high Methods for constructing an antibody having specificity for risk HPV, and relates to an antibody obtained by the method.