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A method of stimulating gastrointestinal motility using growth hormone secretagogues

机译:一种使用生长激素促分泌剂刺激胃肠蠕动的方法

摘要

The present invention relates to a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders or diseases) of the gastrointestinal system. The method comprises administering to a subject in need thereof a therapeutically effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof. The growth hormone secretagogue can be co-administered with a laxative, a HSUB2 /SUBreceptor antagonist, a serotonin 5-HTSUB4 /SUBagonist, an antacid, an opioid antagonist, a proton pump inhibitor, a motilin receptor agonist, dopamine antagonist, a cholinergic agonist, a cholinesterase inhibitor, somatostatin, octreotide, or any combination thereof.
机译:本发明涉及一种在有需要的受试者中刺激胃肠系统的运动的方法,其中该受试者患有胃肠系统的疾病(即疾病或疾病)。该方法包括向有需要的受试者施用治疗有效量的生长激素促分泌素化合物或其药学上可接受的盐,水合物或溶剂化物。生长激素促分泌剂可以与泻药,H 2 受体拮抗剂,5-羟色胺5-HT 4 激动剂,抗酸剂,阿片样物质拮抗剂,质子共同给药泵抑制剂,胃动素受体激动剂,多巴胺拮抗剂,胆碱能激动剂,胆碱酯酶抑制剂,生长抑素,奥曲肽或其任意组合。

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