Rapidly dispersible particulate film coating composition characterized by specific physical stability and low surface roughness based on polyvinyl alcohol-polyether graft copolymer in powder form and without tendency to segregation

摘要

A rapidly dispersible, fine-particle film-coating composition which is in powder form and is not prone to segregation for coating pharmaceutical dosage forms, consisting of a) 40-90% by weight of a polyvinyl alcohol-polyether graft copolymer (component A), b) 1-20% by weight of a polyvinylpyrrolidone or of a vinylpyrrolidone-vinyl acetate-copolymer with a K value of from 10 to 100 (component B) c) 10-60% by weight of organic or inorganic pigments having an average particle size of less than 8 mum (component C) d) 0.5-15% by weight of a surfactant having an HLB of greater than 10 (component D) and e) 0-30% by weight of further customary coating ingredients (components E), in which the particles of component C are embedded in a coherent polymer matrix, where the total amount of components A to E is 100% by weight.