Monoclonal antibody SC104 and its derivatives that specifically bind to sialyltetraaosyl sugars as potential anti-tumor therapeutic agents

摘要

The present invention provides an isolated specific binding member capable of binding a sialyltetraosyl carbohydrate and directly inducing cell death without the need for immune effector cells. Such a binding member may be an antibody or a part thereof. Also provided are the use of such binding members in medicine and nucleic acids encoding such binding members.