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Chemical compound and the dioleoyl phosphatidyl ethanolamine which are displayed

机译:显示的化合物和二油酰基磷脂酰乙醇胺

摘要

Cationic cytofectins and liposomes comprising the same are disclosed which are especially useful for delivering exogenous compounds into cells in vitro and in vivo. The liposomes may comprise (a) a neutral lipid such as dioleoylphosphatidyl-ethanolamine (DOPE) or similar lipid-like compounds such as 1,2-dioleoyl-oxiphosphatidylethanolamine or other lipid-like structures and (b) one or more of the cationic cytofectins provided herein. The invention provides transfection kits and methods for delivery of exogenous compounds into cells.
机译:公开了阳离子细胞转染剂和包含其的脂质体,其对于在体外和体内将外源性化合物递送到细胞中特别有用。脂质体可包含(a)中性脂质,例如二油酰基磷脂酰乙醇胺(DOPE)或类似的脂质样化合物,例如1,2-二油酰基-氧代磷脂酰乙醇胺或其他脂质样结构,以及(b)一种或多种阳离子细胞转染蛋白本文提供。本发明提供了用于将外源化合物递送到细胞中的转染试剂盒和方法。

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