Provide drugs that are useful for preventing the transition to surgical treatment for benign prostatic hyperplasia. The present invention relates to a pharmaceutical composition for preventing transition to surgical treatment of benign prostatic hyperplasia characterized by containing an indoline derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof: (In the formula, R is a substituted aliphatic acyl group, a hydroxyalkyl group, an aliphatic acyloxyalkyl group, a substituted lower alkyl group, a substituted aromatic acyl group, a furoyl group, a pyridylcarbonyl group, etc., and R1 is a cyano group or A carbamoyl group, and R2 represents a substitutable lower alkyl group. [Chemical 1]
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机译:提供可用于预防良性前列腺增生手术治疗的药物。本发明涉及一种用于预防向良性前列腺增生转变为手术治疗的药物组合物,其特征在于,其包含以下通式(I)表示的吲哚啉衍生物或其药理学上可接受的盐:(式中,R为取代的脂肪族化合物。 R 1为氰基或氨基甲酰基,R 1为酰基,羟烷基,脂族酰氧基烷基,取代的低级烷基,取代的芳族酰基,糠酰基,吡啶基羰基等,R 1为氰基或氨基甲酰基。可取代的低级烷基[化学物质1]
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