首页>
外国专利>
Novel salt of RU ((III)) anion complex as antimetastatic agent and antineoplastic agent
Novel salt of RU ((III)) anion complex as antimetastatic agent and antineoplastic agent
展开▼
机译:RU((III))阴离子络合物的新型盐作为抗转移剂和抗肿瘤剂
展开▼
页面导航
摘要
著录项
相似文献
摘要
A salt of an anionic complex of Ru(III) with an ammonium cation fof formula (I),where R1, R2 and R3, equal or different from each other, are selected from the group consisting of H, C1-C6 alkyl, linear or branched, saturated or unsaturated, C3-C7 cycloalkyl, phenyl and aryl; or NR1R2R3 is a 5-7-membered nitrogen-containing heterocycle, saturated or unsaturated, optionally containing one or more O, S and/or N atoms, said nitrogen atom being optionally substituted with a C1-C4 alkyl, aryl or benzyl residue; said nitrogen-containing heterocycle being optionally condensed with a benzo group and/or substituted with C1-C4 alkyl, C1-C4 alkoxyl, C1-C4 alkylthio, aryl or benzyl groups; where R4 and R5, equal or different from each other, are selected from the group consisting of H, C1-C6 alkyl, C3-C7 cycloalkyl, phenyl and aryl or R4 and R5 form, together with the S atom, a 4-7-membered heterocycle. Furthermore the process for the preparation of said salts, the pharmaceutically compositions containing the same and their use as antimetastatic and antineoplastic agents are described.
展开▼