Method for evaluating uniformity of suplatast tosilate crystal, uniform crystal and method for producing the same

摘要

A method for evaluating the uniformity of suplatast tosylate crystals, a crystal with uniform and stable optical purity, and a method for producing the same. In the method for evaluating the uniformity of suplatast tosylate crystals, (a) adding a solvent to the suplatast tosylate crystals to dissolve 3% or less of that amount, measuring a portion of the resulting suspension supernatant and measuring the optical purity (B) Next, a solvent is added to the remaining suspension to dissolve the whole amount, and a part of the solution is taken to measure the optical purity. The steps (a) and (b) A method for evaluating the uniformity of a suplatast tosylate crystal characterized by comparing the optical purity of the splatast tosilate crystal and a method for producing the same.