Muscle relaxation promoter and therapeutic agent for diseases related to muscle tissue such as muscle relaxation failure

摘要

Muscle relaxation promoter, therapeutic agent for left ventricular diastolic dysfunction, therapeutic agent for angina pectoris, therapeutic agent for acute pulmonary edema, blood flow improving agent for microcirculatory system and therapeutic agent and prophylactic agent for hypertension, ventricular tachycardia and torsadopoan The present invention provides a drug that can be used as a therapeutic agent and a preventive agent. The drug is represented by the general formula [I] [Wherein R ¹ represents hydrogen or a lower alkoxy group having 1 to 3 carbon atoms, R ² represents hydrogen, a lower alkoxy group having 1 to 3 carbon atoms, or a phenyl group (where the phenyl group is a hydroxyl group or 1 to 3 carbon atoms) 3 may be substituted with 1 to 3 substituents selected from the group consisting of 3 lower alkoxy groups). (Wherein R ³ is an acyl group having 1 to 3 carbon atoms), X represents —CO— or —CH 2 —, and n represents 1 or 2. And a pharmaceutically acceptable salt thereof as an active ingredient.