METHOD FOR TRAINING OF SUPERVISED PROTOTYPE NEURAL GAS NETWORKS AND THEIR USE IN MASS SPECTROMETRY

摘要

A Neural Gas network used for pattern recognition, sequence and image processing is extended to a supervised classifier with labeled prototypes by extending a cost function of the Neural Gas network with additive terms, each of which increases with a difference between elements of the class labels of a prototype and a training data point and decreases with their distance. The extended cost function is then iteratively minimized by adapting weight vectors of the prototypes. The trained network can then be used to classify mass spectrometric data, especially mass spectrometric data derived from biological samples.