Method for Providing an InVivo Model of Disc Degeneration

摘要

A method for providing an InVivo model of disc degeneration. The method includes percutaneously inserting a needle into a non-human surrogate disc, generally the disc of a rabbit, so that the needle ruptures the annulus of the disc. Fluoroscopy X-ray images can be used to visualize the placement of the needle to the proper location. By using the proper surrogate, rupture of the annulus of the disc will have a quick degenerative effect on the disc, which can be visualized using MRI or other suitable imaging devices. By studying the etiologies associated with disc degeneration of the surrogate, treatments can then be devised to attempt to reduce the rate of degeneration, reverse degeneration, or other disc treatment procedures.