Apparatuses, Systems, and Methods Utilizing Laminar Flow Interface Control and for Controlling Laminar Flow Interface

摘要

Apparatuses, systems, and methods for controlling the position of the interface between two or more laminar flow stream in a microfluidic device. In one embodiment, an apparatus includes a first fluid reservoir shaving an output, a first pressure sensor connected to the output of the first fluid reservoir, a first actuator connected to the first fluid reservoir, a feedback loop connected between the first pressure sensor and the first actuator, a second fluid reservoir having an output, a second pressure sensor connected to the output of the second fluid reservoir, a second actuator connected to the second fluid reservoir, a feedback loop connected between the second pressure sensor and the second actuator, and a microfluidic device including a first input connected to the output of the first fluid reservoir, a second input connected to the output of the second fluid reservoir, and an output. In another embodiment, a method includes sensing fluid pressure from a first fluid reservoir connected to a first input of the microfluidic device, adjusting a first actuator in response to the fluid pressure in the first fluid reservoir, sensing fluid pressure from a second fluid reservoir connected to a second input of the microfluidic device, and adjusting a second actuator in response to the fluid pressure in the second fluid reservoir.